Endocrine Abstracts

We describe a case of severe rhabdomyolysis(peak CK 48897 μ/ml and massive myoglobinuria) complicating hyperglycemic hyperosmolar coma. A 57y/o M with DM2 on metformin presented with polyuria, polydipsia, weakness and confusion. On admission he had GCS E2M3V1 no signs of trauma or infection. Na 137 mEq/l K 4.8 mEq/l HCO3 22 mEq/l Cl 93 mEq/l BUN 116 mg/dl Cr 3.2 mg/dl glucose 1710 mg/dl pH 7.22 ketones +small, Mg 5.2 mg/dl P 3.3 mg/dl Ca 9.6 mg/dl TSH 1.47 &#95...

We describe a case of aggressive pituitary adenoma with atypical biological behavior treated with surgery radiation & chemotherapy. A 46 y/o F presented with nausea & acute vision loss R>L,with no symptoms of amenorrhea, hypothyroidism or hypoadrenalism. Brain MRI showed 4.7×3.6×3.6 cm pituitary macroadenoma with mass effect on optic chiasm, cavernous sinus extension, internal carotid artery encasement, extension into R foramen ovale, orbital apex, spheno...

We describe the course of a now 24y/o M with congenital hypopituitarism, severe micropenis, cryptorchidism, hypoplastic testes, hypospadiasis and pulmonic stenosis. He presented with neonatal hypoglycemia. MRI showed small anterior pituitary and ectopic posterior pituitary near tuberous cinereum. Pulmonic stenosis detected after auscultation of a murmur, was mild grade on echo. Free T4 1 ng/dl (1–2.5) TSH 6.7 μU/ml (0.2–6) glucagon stimulation for GH ...